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. 2015 Jun 26;5:11596. doi: 10.1038/srep11596

Figure 6. Effect of ebselen on cytokines production in MRSA skin lesions.

Figure 6

Supernatants from skin homogenates were used for cytokine detection by ELISA. Each points represents single mice and each group has 5 mice. Statistical analysis was calculated by the two-tailed Student t test. P values of (*P ≤0.05) (**P ≤ 0.01) are considered as significant. Detailed P values are listed: IL-1β: Control vs 2% linezolid, 0.0054; Control vs 1% ebselen, 0.0026; Control vs 2% ebselen, 0.0007. IL-6: Control vs 0.5% ebselen, 0.0011; Control vs 1% ebselen, 0.0055; Control vs 2% ebselen, 0.0006. TNF-α: Control vs 1% ebselen, 0.0424; Control vs 2% ebselen, 0.0164. MCP-1: Control vs 0.5% ebselen, 0.0004; Control vs 1% ebselen, 0.0325; Control vs 2% ebselen, 0.0001.