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. 2015 Jun 26;5:11596. doi: 10.1038/srep11596

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Copyright © 2015, Macmillan Publishers Limited

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The Bliss Model for Synergy confirms a synergistic effect, between ebselen and topical antimicrobials (mupirocin, fusidic acid, retapamulin and daptomycin) against various resistant strains of S. aureus. Degree of synergy was quantified after 12 h of treatment with ebselen (0.0312 μg/ml) in combination with sub-inhibitory concentrations of topical antimicrobials. (Circle) daptomycin + ebselen, (Square) retapamulin + ebselen, (Triangle) fusidic acid + ebselen and (Inverted triangle) mupirocin + ebselen.