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. 2015 Jun 25;10(6):e0127419. doi: 10.1371/journal.pone.0127419

Table 1. Comparative ultrasonography indicator analysis of the Targeted NBs and Blank NBs in 3 types of xenografts.

Contrast Agents Arrival Time (s) Time to Peak (s) Peak Intensity (dB) Imaging Duration (min)
LNCaP tumor Blank NBs 2.40±0.03 9.41±0.11 19.62±0.44 20.20±0.28
Targeted NBs 2.42±0.09 # , + 9.40±0.22 + 21.47±0.60 * , # , + 22.58±0.74 *
C4-2 tumor Blank NBs 2.30±0.02 9.06±0.10 19.20±0.40 21.29±0.52
Targeted NBs 2.32±0.07 # 9.05±0.12 # 20.52±0.44 * , # 23.00±0.33 *
MKN45 tumor Blank NBs 2.20±0.02 9.40±0.12 18.46±0.29 22.14±0.56
Targeted NBs 2.21±0.03 9.38±0.10 18.50±0.33 22.23±0.53

The data are presented as the means ± SD (n = 5).

*P <0.05 indicates the level of significance compared with Blank NBs in the same types of xenografts;

#P <0.05 indicates the level of significance compared with targeted NBs in the gastric cancer xenografts (MKN45);

+P <0.05 indicates the level of significance compared with targeted NBs in the C4-2 xenografts.