Table 2.
Multivariate analysis of risk factors related to survival in patients with hepatocellular carcinoma rupture
| Variables | HR | 95%CI | P value |
| Age (yr) | 0.96 | 0.93-1.00 | 0.026 |
| Lesion length (cm) | 1.46 | 1.23-1.73 | < 0.001 |
| Number | 1.37 | 1.01-1.85 | 0.042 |
| Cirrhosis (presence) | 2.47 | 0.77-7.96 | 0.131 |
| BCLC stage A (control) | - | - | - |
| BCLC stage B | 0.10 | 0.02-0.41 | 0.002 |
| BCLC stage C | 0.19 | 0.03-1.01 | 0.052 |
| Treatment before rupture (presence) | 4.36 | 1.27-14.99 | 0.019 |
| Treatment in follow-up period (presence) | 0.21 | 0.07-0.67 | 0.008 |
| WBC, × 109/L | 1.04 | 0.96-1.13 | 0.375 |
| HB, g/L | 0.99 | 0.97-1.00 | 0.314 |
| PLT, × 1010/L | 1.00 | 0.99-1.00 | 0.143 |
| INR | 0.39 | 0.04-3.60 | 0.406 |
| APTT, S | 1.07 | 0.99-1.15 | 0.103 |
| ALT, U/L | 1.00 | 1.00-1.01 | 0.011 |
| ALB, g/L | 0.89 | 0.81-0.97 | 0.010 |
| TBil, umol/L | 1.00 | 0.97-1.02 | 0.735 |
| HCO3-, mmol/L | 1.18 | 1.08-1.28 | < 0.001 |
| Crea, umol/L | 1.01 | 1.00-1.02 | 0.089 |
| Child-Pugh | 1.03 | 0.59-1.80 | 0.905 |
WBC: White blood cell count; HB: Hemoglobin; PLT: Platelet count; INR: International normalized ratio; APTT: Activated partial thromboplastin time; ALT: Alanine transaminase; ALB: Albumin; TBil: Total bilirubin; HCO3-: Bicarbonate; Crea: Creatinine.