Table 4. Pooled positive rate of various serum markers in Chinese AIP patients.
Tests of Heterogeneity | Tests of Publication Bias | |||||||
---|---|---|---|---|---|---|---|---|
Serum markers | Studies No | Positive Cases / Total Cases | Pooled Positive Rate, % (95%CI) | Q Value | P | I 2(%) | Begg’s P | Egger’s P |
IgG4 a | 9 | 170/195 | 86.0(74.2–94.6) | 31.71 | 0.0001 | 74.8 | 0.0446 | 0.0265 |
IgG b | 19 | 257/391 | 70.3(60.6–79.1) | 74.87 | <0.0001 | 76 | 0.195 | 0.3595 |
IgE c | 4 | 49/113 | 61.8(23.7–92.9) | 37.6 | <0.0001 | 91.9 | 0.75 | 0.7564 |
γ-globulin | 12 | 154/225 | 67.9(56.9–78.0) | 34.67 | 0.0003 | 68.3 | 0.0138 | 0.0019 |
Rheumatoid factor | 6 | 34/110 | 35.7(20.7–52.2) | 14.75 | 0.0115 | 66.1 | 0.2722 | 0.0517 |
ANA d | 13 | 83/266 | 33.3(24.8–42.4) | 29.21 | 0.0037 | 58.9 | 0.0573 | 0.074 |
ESR e | 7 | 65/109 | 59.4(50.4–68.2) | 10.20 | 0.1163 | 41.2 | 0.1668 | 0.0051 |
CA19-9 | 18 | 178/411 | 41.5(34.9–48.3) | 32.16 | 0.0144 | 47.1 | 0.9697 | 0.3708 |
aImmunoglobulin G4
bImmunoglobulin G
cImmunoglobulin E
A
dAnti-neutrophil antibody
eErythrocyte sedimentation rate