β
|
Rate of bacterial transmission |
0.01–0.5 day-1 [28,29] |
pi
|
Probability of developing resistance to antibiotic i during treatment |
0–0.3 [30,31] |
γ
|
Rate of clearance due to the patient's immune system |
0.03 day-1
|
τ(1−pi) |
Rate of clearance due to antibiotic i
|
day-1 [20] |
c
|
Rate of patient turnover (length of stay-1) |
0.1 day-1 [28] |
λV
|
Entrance rates of patients of class V |
Varies (day-1 units) |
fV
|
Resistance frequency of incoming patients, of the class V |
Varies |
|
Resistance frequency of incoming patients, of the restricted antibiotic (antibiotic 3) |
0.001 [32,33] |
d
|
Delay of correct treatment factor |
0.778 [34] |
π
|
Hospital size relative to community |
[35] |
Χi
|
Fraction of patients initially treated with antibiotic i
|
Determined by strategy |
|
Fraction of patients treated with antibiotic i, for which resistance to antibiotic k ≠ i, j was established. |
Varies |
t1–t0 |
Duration of time the dynamics are tested for. |
20–100 years |