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. 2015 Jun 25;11(6):e1004340. doi: 10.1371/journal.pcbi.1004340

Table 1. Parameters, their meaning and values.

Parameter Meaning Value
β Rate of bacterial transmission 0.01–0.5 day-1 [28,29]
pi Probability of developing resistance to antibiotic i during treatment 0–0.3 [30,31]
γ Rate of clearance due to the patient's immune system 0.03 day-1
τ(1−pi) Rate of clearance due to antibiotic i 17 day-1 [20]
c Rate of patient turnover (length of stay-1) 0.1 day-1 [28]
λV Entrance rates of patients of class V Varies (day-1 units)
fV Resistance frequency of incoming patients, of the class V Varies
fR3 Resistance frequency of incoming patients, of the restricted antibiotic (antibiotic 3) 0.001 [32,33]
d Delay of correct treatment factor 0.778 [34]
π Hospital size relative to community 1300 [35]
Χi Fraction of patients initially treated with antibiotic i Determined by strategy
χi,ji Fraction of patients treated with antibiotic i, for which resistance to antibiotic ki, j was established. Varies
t1–t0 Duration of time the dynamics are tested for. 20–100 years