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. 2015 Jun 25;11(6):e1005167. doi: 10.1371/journal.pgen.1005167

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© 2015 Burla et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 8 — (A) Immunolocalization of AKTIP in HPFs and HeLa cells with an anti-AKTIP antibody, and in AKTIP-FLAG expressing 293T cells with an anti-FLAG antibody. shAKTIP HPFs show a strong reduction of the AKTIP signal. (B) Optical sections of a HPF and a HeLa cell showing AKTIP enrichment at the nuclear periphery. (C) Co-immunostaining of detergent-extracted HPFs for AKTIP and TRF1 (projection of 8 z stacks) showing a limited signal co-localization.