Table 3.

Multivariable-adjusted^a hazard ratios (HR) and 95% confidence intervals (CI) for the associations of measures of body size with risk of head and neck cancer by cigarettes per day (CPD) in current smokers and years since quitting in former smokers

	Height (per 5 cm) HR (95% CI) P for trend	Body mass index (per 5 kg/m2) HR (95% CI) P for trendb	Waist circumference (per 5 cm) HR (95% CI) P for trend	Hip circumference (per 5 cm) HR (95% CI) P for trend	Waist-to-hip ratio (per 0.1 unit) HR (95% CI) P for trend
Cigarettes per day (CPD) in current smokers
<20	0.94 (0.82–1.07)	0.79 (0.61–1.03)	0.99 (0.90–1.08)	0.87 (0.77–0.99)	1.30 (1.00–1.70)
	0.32	0.079	0.82	0.031	0.054
20–<30	0.98 (0.86–1.11)	0.72 (0.56–0.92)	0.99 (0.91–1.07)	0.82 (0.73–0.92)	1.43 (1.16–1.76)
	0.69	0.0085	0.76	0.0008	0.0009
≥ 30	1.04 (0.89–1.23)	0.61 (0.44–0.84)	0.90 (0.81–1.00)	0.79 (0.69–0.91)	1.07 (0.78–1.46)
	0.60	0.0025	0.060	0.0010	0.67
P-value for interaction	0.76	0.06	0.01	0.26	0.01
Years since quitting in former smokers
<10	1.02 (0.96–1.09)	0.82 (0.73–0.92)	0.98 (0.93–1.04)	0.92 (0.86–0.99)	1.09 (0.94–1.27)
	0.46	0.0006	0.57	0.032	0.23
10–<20	1.13 (1.02–1.26)	0.93 (0.77–1.12)	1.01 (0.92–1.10)	1.01 (0.88–1.15)	1.09 (0.80–1.47)
	0.025	0.44	0.86	0.93	0.60
20+	1.00 (0.89–1.12)	1.15 (0.96–1.37)	1.09 (0.99–1.19)	1.12 (0.97–1.30)	1.11 (0.78–1.58)
	0.99	0.13	0.073	0.12	0.56
P-value for interaction	0.77	0.006	0.20	0.10	0.83

^aMultivariable-adjusted models included age, sex, genetic ancestry, cohort, education and alcohol drinking status.

^bThe P-value for linear trend was calculated excluding the underweight category.