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. 2015 Mar 3;7(2):92–104. doi: 10.1093/jmcb/mjv014

Figure 2.

Figure 2

Functions of ribosome-free RPs in response to RS. RS unleashes many free forms of RPs that are involved in tumorigenesis or immune response by regulating multiple signaling pathways. Additionally, impairment of ribosomal biogenesis through mutation or deregulation of RP-encoding genes leads to ribosomopathies and developmental defects.