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Optical detection of HIV-1 virus based on LSPR mechanism. (A) Schematic representation of the immunoassay configuration with LSPR method for the quantitative detection of HIV-1 particles; (B). Optical characteristics (change in absorbance peak) based on the: (a) bare Au nanopattern on ITO substrate; (b) fragmented antibody immobilized layer; (c) blocking with casein; (d) HIV-1 VLPs immuno reacted layer. Figure reproduced with permission from [40], © 2013 Elsevier.
