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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Obesity (Silver Spring). 2015 Jul;23(7):1493–1501. doi: 10.1002/oby.21111

Table 3.

Top CpG methylation sites associated with waist circumference in GOLDN (n=991) and ARIC (n=2,106) at the level of genome-wide significance (P<1.1×10−7 ) in the discovery phase.

Marker Chr Gene Discovery (GOLDN) Replication (ARIC) Meta P
P SE P P SE P
cg00574958 11 CPTIA −0.0003 0.00005 2.6×10−10 −0.004 0.0007 2.1×10−8 2.2×10−16
cg04332373 4 CD38 0.0005 0.00008 6.2×10−10 0.004 0.0009 0.00003 6.1×10−13
cg07504977 10 NA 0.0004 0.00007 7.6×10−9 0.005 0.002 0.003 5.8×10−10
cg25349939 2 GTDC1 0.0005 0.00008 1.6×10−8 0.0009 0.0008 0.26 8.4×10−8
cg14476101 1 PHGDH −0.0006 0.0001 1.7×10−8 −0.003 0.002 0.06 2.2×10−8