Table 2. Stability of the alphoidtetO-HAC/tTAVP64 in dox+ and dox− medium in hamster CHO and human HeLa cells.
Hamster ovary CHO cells | |||
---|---|---|---|
# clonea | Medium | 3 days | 14 days |
1 | dox+ | 99% | 77% |
dox− | 99% | 4% | |
2 | dox+ | 99% | 85% |
dox− | 99% | 5% | |
Human epithelium HeLa cells | |||
1 | dox+ | 99% | 93% |
dox− | 99% | 2% | |
2 | dox+ | 99% | 92% |
dox− | 99% | 3% |
aFor each HAC-containing clone at least 130–140 metaphases were examined.