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. 2015 Apr 8;43(9):4733–4745. doi: 10.1093/nar/gkv296

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© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — G-rich telomeric DNA from C. elegans and humans forms fundamentally different structures. LEFT: CD spectra of the DNA constructs based on human (A) and C. elegans (C) G-rich telomeric DNA repeats as a function of the number of telomeric repeats and/or the presence of the 3′-flanking residue. The insets display the thermal difference spectra (TDS) of each construct (58). CENTRE: Imino regions of the 1D ¹H NMR spectra of the DNA constructs based on human (B) and C. elegans (D) G-rich telomeric DNA repeats showing the effect of the number of telomeric repeats and the presence of the 3′-flanking residue (C. elegans). RIGHT: Structural interpretation of the spectra.