Fig. 4.

Functional classification of the products encoded by the divergent neighbouring genes. Genes that were divergently oriented to TFTRs with an intergenic region of 200 bp or less in M. tuberculosis, M. marinum, M. avium paratuberculosis and M. smegmatis were analysed as described in the materials and methods. Gene products that were enzymes were classified according to class (EC 1 to EC 6). Non enzymatic products were classified into membrane proteins, other proteins (e.g. transcriptional regulators), and proteins of unassigned function