Table 2. Technology comparison of NRBC enrichment efficiencies.
| Study | Pregnancy status | Number of cases | Gestational age (weeks) | Mean cells/mL | Median cells/mL | Range cells/mL | Method |
|---|---|---|---|---|---|---|---|
| Artemis Health | Singleton | 37 | 9–22 | 37.68 | 21.08 | 0.37–168.27 | CSM/HE |
| Abnormal | 21 | 11–21 | 37.20 | 18.13 | 0.99–274.36 | CSM/HE | |
| Slunga-Tallberg et al., 1995 | Singleton | 37/40 | 6–17 | 0.63 | 0.20 | 0.05–11.50 | miniMACS |
| Takabayashi et al., 1995 | Not Given | 33/60 | 4–40 | 2.05 | — | 0.50–11.00 | Density gradient |
| Babochkina et al., 2005 | Not Given | 11 | 11–40 | — | 16.00 | 2.00–59.00 | SBA-Lectin |
| 11 | 11-40 | — | 2.00 | 0.00–6.00 | MACS | ||
| Purwosunu et al., 2006b | Singleton | 22 | 9–34 | — | 2.08 | 0.16–13.66 | Galactose–Lectin |
| Post-termination | 23 | 6–19 | — | — | — | Galactose–Lectin | |
| Mavrou et al., 2007 | Normal (preamnio) | 282 | 14–28 | 0.40 | — | 0.05–0.60 | MACS |
| Abnormal (postamnio) | 23 | 14–28 | 1.75 | — | 0.35–5.65 | MACS | |
| Carriers B-thal | 26 | 14–28 | 2.10 | — | 1.10–7.90 | MACS | |
| Abnormal Doppler | 20 | 14–28 | 0.75 | — | 0.10–3.75 | MACS | |
| Sekizawa et al., 2007 | Singleton | 20 | 10–18 | 0.91 | 0.97 | 0.17–1.69 | Galactose–Lectin |
| Kwon et al., 2007 | Normal | 24 | 11–24 | 1.95 | 1.55 | 0.20–4.80 | Double density gradient/MACS |
| Abnormal | 1 | 13 | 5.40 | — | — |
CSM, cell separation microchip; HE, hemoglobin enrichment; MAC, magnetic-activated cell sorting.