Table 6. Relative risks (and 95% CIs) of colorectal cancer by quintile (Q) of carbohydrate for each ethnic group (multivariate model 2 only)1.
| Cases | Q2 | Q3 | Q4 | Q5 | P for trend | |
|---|---|---|---|---|---|---|
| n | ||||||
| Men2 | ||||||
| African American | 166 | 1.10 (0.69, 1.76) | 1.31 (0.80, 2.15) | 1.08 (0.60, 1.95) | 1.31 (0.69, 2.50) | 0.452 |
| Japanese American | 491 | 1.15 (0.78, 1.69) | 1.13 (0.76, 1.68) | 0.96 (0.63, 1.47) | 0.97 (0.61, 1.53) | 0.460 |
| Latino | 172 | 0.82 (0.55, 1.24) | 0.89 (0.57, 1.39) | 0.91 (0.55, 1.49) | 1.06 (0.60, 1.88) | 0.787 |
| White | 259 | 1.10 (0.73, 1.65) | 1.40 (0.91, 2.17) | 1.66 (1.04, 2.68) | 1.38 (0.77, 2.48) | 0.089 |
| Women3 | ||||||
| African American | 300 | 1.10 (0.76, 1.59) | 1.04 (0.69, 1.58) | 1.02 (0.64, 1.63) | 0.66 (0.36, 1.22) | 0.339 |
| Japanese American | 335 | 0.69 (0.42, 1.13) | 0.74 (0.46, 1.21) | 0.68 (0.41, 1.11) | 0.61 (0.35, 1.09) | 0.139 |
| Latina | 168 | 0.87 (0.53, 1.41) | 0.84 (0.49, 1.43) | 0.88 (0.49, 1.58) | 0.53 (0.25, 1.15) | 0.182 |
| White | 216 | 0.90 (0.57, 1.42) | 1.15 (0.71, 1.84) | 0.79 (0.46, 1.40) | 0.65 (0.33, 1.31) | 0.275 |
Energy-adjusted carbohydrate intakes were determined by the residual method. Q2 through Q5 adjusted carbohydrate intake were 43.7 to <48.9, 48.9 to <53.4, 53.4 to <59.1, and ≥59.1 g · 1000 kcal−1 · d−1, respectively, in men and 45.1 to <50.4, 50.4 to <55.0, 55.0 to <60.5, and ≥60.5 g · 1000 kcal−1 · d−1, respectively, in women. In the multivariate model 2, Cox regression models adjusted for age, ethnicity, time since cohort entry, family history of colorectal cancer, history of colorectal polyp, pack-years of cigarette smoking, BMI, hours of vigorous activity, nonsteroidal anti-inflammatory drug use, multivitamin use, energy intake (logarithmically transformed), replacement hormone use (women only), and alcohol, red meat, folate, vitamin D, calcium and dietary fiber intakes.
P for interaction = 0.013.
P for interaction = 0.725.