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. Author manuscript; available in PMC: 2015 Jun 26.
Published in final edited form as: Physiol Rev. 2009 Oct;89(4):1379–1412. doi: 10.1152/physrev.00005.2009

Fig. 2.

Fig. 2

Schematic representation of the brain reinforcement circuit. Brain sites of reinforcement are integrated in a circuit based on their connectivity and putative functional roles. BNST, bed nucleus of the stria terminalis; CPu, caudate putamen; LH, lateral hypothalamus; mPFC, medial prefrontal cortex; NAc, nucleus accumbens; PAG, periaqueductal gray; POA, preoptic area; VP, ventral pallidum; VTA, ventral tegmental area. [Adapted from Kelley (183) and Koob and Le Moal (202).]