Table 4.

Results of Overall Survival Analysis by Cox Proportional Hazards Model for the untreated subgroup

Prognostic Factor		Univariate (n = 142)		Multivariate (n = 129c)
		HR (95 % CI)	P-value	HR (95 % CI)	P-value
Menacalc
	High vs. Low	2.14 (1.05, 4.58)	0.0445	3.80 (1.58, 9.97)	0.0052
Her2a
	Positive vs. Negative	1.59 (0.43, 4.31)	0.4234	1.35 (0.34, 4.02)	0.6376
Tumor Size
	≥2 cm vs. <2 cm	2.05 (1.01, 4.22)	0.0508	1.41 (0.62, 3.23)	0.4178
ERa
	Negative vs. Positive	1.62 (0.68, 3.51)	0.2504	0.99 (0.36, 2.51)	0.9863
PR*
	Positive vs. Negative	2.84 (1.27, 7.05)	0.0173	NAb	NAb
Histological grade
	Grade 2-3 vs. Grade 1	2.61 (1.09, 7.43)	0.0505	1.85 (0.67, 5.84)	0.2719
	ND vs. Grade 1	1.46 (0.39, 5.23)	0.5667	1.34 (0.33, 5.03)	0.6763
Lymphatic invasion
	Present vs. Absent	2.11 (0.81, 4.75)	0.0993	1.63 (0.54, 4.16)	0.3537
Age, years
	≥50 vs. <50	2.41 (1.03, 6.77)	0.0666	3.03 (1.17, 9.11)	0.0348

^aIHC marker

^bPR was not included as ER and PR are correlated

^cTumors excluded if missing data for either Her2 or ER