Table 4.
Biochemical changes in the studied groups
| Pre treatment | 2 weeks | 1 month | 2 months | 3 months | 6 months | 9 months | 12 months | |
|---|---|---|---|---|---|---|---|---|
| Albumin | ||||||||
| Control | 2.80 ± 0.15 | 2.80 ± 0.14 | 2.75 ± 0.19 | 2.73 ± 0.18 | 2.71 ± 0.21 | 2.68 ± 0.22 | 2.66 ± 0.22 | 2.64 ± 0.19 |
| Single infusion | 2.58 ± 0.15 | 2.70 ± 0.22 | 2.79 ± 0.22 | 2.90 ± 0.24* | 2.96 ± 0.35* | 2.98 ± 0.33* | 2.95 ± 0.33* | 2.88 ± 0.30* |
| Double infusion | 2.84 ± 0.17 | 2.95 ± 0.13# | 3.04 ± 0.14# | 3.16 ± 0.14#* | 3.28 ± 0.17#* | 3.36 ± 0.20#* | 3.39 ± 0.20#* | 3.39 ± 0.21#* |
| s-Bilirubin | ||||||||
| Control | 3.19 ± 0.89 | 3.23 ± 0.87 | 3.31 ± 0.92 | 3.32 ± 0.92 | 3.33 ± 0.92 | 3.36 ± 0.91 | 3.30 ± 0.88 | 3.24 ± 0.78 |
| Single infusion | 3.59 ± 0.79 | 3.43 ± 0.77 | 3.39 ± 0.76 | 3.29 ± 0.83 | 3.18 ± 0.88 | 3.10 ± 0.93* | 3.16 ± 0.81 | 3.18 ± 0.84# |
| Double infusion | 3.16 ± 0.99 | 3.07 ± 0.95 | 3.03 ± 0.96 | 2.96 ± 0.94 | 2.86 ± 0.98* | 2.76 ± 0.98#* | 2.77 ± 1.00#* | 2.75 ± 0.98#* |
| INR | ||||||||
| Control | 1.67 ± 0.16 | 1.62 ± 0.19 | 1.61 ± 0.21 | 1.67 ± 0.19 | 1.73 ± 0.19 | 1.73 ± 0.21 | 1.74 ± 0.20 | 1.72 ± 0.20 |
| Single infusion | 1.76 ± 0.22 | 1.60 ± 0.32 | 1.54 ± 0.33 | 1.46 ± 0.34* | 1.42 ± 0.36* | 1.44 ± 0.34* | 1.46 ± 0.29* | 1.49 ± 0.28* |
| Double infusion | 1.68 ± 0.17 | 1.60 ± 0.20 | 1.57 ± 0.22 | 1.53 ± 0.22 | 1.49 ± 0.16* | 1.44 ± 0.17* | 1.43 ± 0.18* | 1.41 ± 0.15* |
| Serum creatinine | ||||||||
| Control | 1.06 ± 0.15 | 0.95 ± 0.10 | 0.94 ± 0.06 | 0.95 ± 0.09 | 0.96 ± 0.14 | 0.95 ± 0.11 | 0.93 ± 0.99 | |
| Single infusion | 0.92 ± 0.13 | 0.90 ± 0.15 | 0.92 ± 0.17 | 0.88 ± 0.16 | 0.89 ± 0.16 | 0.91 ± 0.12 | 0.89 ± 0.11 | |
| Repeated infusion | 1.04 ± 0.16 | 0.93 ± 0.10 | 0.91 ± 0.11 | 0.91 ± 0.09 | 0.90 ± 0.13 | 0.91 ± 0.22 | 0.92 ± 0.13 | |
Data presented as mean ± standard deviation
*P <0.05 between single infusion or repeated infusion groups and the control group
# P <0.05 between the single infusion and repeated infusion groups