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. 2015 Jun 26;12:15. doi: 10.1186/s12987-015-0010-1

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© Ishikawa et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Virchow–Robin spaces (VRS) in axial images in the brain of a control subject. Multi-planar reconstruction constructive interference in steady state (CISS) images: VRS in the basal ganglia (a) were round and irregularly sized (small arrows). Enlarged VRS sometimes could be seen as oval pools (arrowheads) in the lower part of the basal ganglia. In the white matter of the periventricular region (b), semioval center (c) and subcortical region (d), VRS were round (small arrows) or tubular (large arrows), and homogeneously sized; observation in an 80-year-old woman.