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. Author manuscript; available in PMC: 2015 Oct 2.
Published in final edited form as: N Engl J Med. 2015 Apr 2;372(14):1333–1341. doi: 10.1056/NEJMoa1406656

Table 2.

Patterns of Demographic and Epidemiologic Change in Cardiovascular Mortality.

Category Change in Cardiovascular Deaths, 1990–2013 Effect of Population Growth Effect of Population Aging Effect of Age-Specific Cardiovascular Death Rate Regions
Category 1 — Population growth and aging: Regions with large and continuous increases in the number of cardiovascular deaths due to population growth or aging but little change in age-specific rates of death Increase Large (≥20%) Large (>30%) Small (decline <30%) Oceania, South Asia, Southeast Asia, Caribbean
Category 2 — Population growth: Regions with increases in deaths due mostly to population growth Increase Large (>80%) Small (<10%) Small (decline <30%) Central sub-Saharan Africa, Western sub-Saharan Africa, Eastern sub-Saharan Africa
Category 3 — Population aging: Regions in which cardiovascular deaths rose and then fell during the preceding 20 years, resulting in a net increase in deaths due to population aging and only a small decrease in age-specific rates of cardiovascular death Increase then decrease Very small (<20%) Moderate (>20%) Very small (decline <15%) Eastern Europe, Central Asia
Category 4 — Improved health moderating effect of population aging: Regions in which large increases in the number of cardiovascular deaths due to population aging were moderated by a fall in age-specific rates of death Increase Small (<30%) Very large (>70%) Large (decline >30%) High-income Asia–Pacific, East Asia
Category 5 — Improved health moderating effect of population growth and aging: Regions with large relative increases in the number of cardiovascular deaths due to both population growth and aging that were moderated by a fall in age-specific rates of death Increase Large (>30%) Large (>30%) Large (decline >30%) Central Latin America, Tropical Latin America, Andean Latin America, Southern sub-Saharan Africa, North Africa and Middle East
Category 6 — Improved health exceeding effect of population growth and aging: Regions in which large declines in age-specific cardiovascular death rates have led to only small increases or even a decline in the number of cardiovascular deaths despite the large effects of an aging population Small increase or decrease Small (<40%) Large (>30%) Large (decline >30%) Southern Latin America, Australasia, high-income North America, Central Europe, Western Europe