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. 2015 Jun 22;8:1543–1552. doi: 10.2147/OTT.S77373

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© 2015 Lu et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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THIO inhibits tumor cell migration and expression of EMT-related genes.

Notes: (A) Transwell analysis for cells (SNU449, LM3, and Huh7) after treatments with THIO. (B) Quantification of migrated cells after transwell assay. *P<0.05, **P<0.01, ***P<0.005. (C–E) RT-PCR analysis of the EMT-related genes in SNU449 (C), LM3 (D), and Huh7 (E) cells after treatment with THIO for 24 hours.

Abbreviations: RT-PCR, real-time polymerase chain reaction; THIO, thioridazine; EMT, epithelial–mesenchymal transition.