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. 2015 Jun 22;9:3163–3178. doi: 10.2147/DDDT.S80958

Figure 8.

Figure 8

Effects of CDDO-Me treatment on expression of selected profibrotic genes in radiation-treated mice.

Notes: Expression levels of three profibrotic genes including fibronectin (A), α-SMA (B) and collagen I (C) were analyzed by real time-polymerase chain reaction in mouse lungs at 12 weeks post-irradiation. The results are shown as the mean ± standard error of the mean of ten mice per group. *P<0.05 and ***P<0.001 by one-way analysis of variance followed by Tukey’s post hoc test.

Abbreviations: CDDO-Me, C-28 methyl ester of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid; α-SMA, α-smooth muscle actin.