Table 1.
STUDY | ADEQUATE SEQUENCE GENERATION | ALLOCATION CONCEALMENT | BLINDING OF PARTICIPANTS, PERSONNEL, AND OUTCOME ASSESSORS | INCOMPLETE OUTCOME DATA ADDRESSED | FREE OF SELECTIVE OUTCOME REPORTING | FREE OF OTHER SOURCES OF BIAS |
---|---|---|---|---|---|---|
Gayda et al. 201233 | ? | ? | ✓ | ✓ | ✓ | ✓ |
Meyer et al. 201134 | ? | ? | ✓ | ✓ | ✓ | ✓ |
Guiraud et al. 201335 | ? | ? | ✓ | × | ✓ | ✓ |
Normandin et al. 201336 | n/a | n/a | ✓ | ✓ | ✓ | ✓ |
Tomczac et al. 201137 | n/a | n/a | ✓ | ✓ | ✓ | ✓ |
Guiraud et al. 201038 | ? | ? | ✓ | ✓ | ✓ | ✓ |
Guiraud et al. 201139 | ? | ? | ✓ | ✓ | ✓ | ✓ |
Currie et al. 201240 | × | ? | ✓ | ✓ | ✓ | ✓ |
Whyte et al.41 | ? | ? | ✓ | ✓ | ✓ | ✓ |
Gillen et al. 201242 | n/a | n/a | ✓ | ✓ | ✓ | ✓ |
Tjonna et al. 201143 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
Notes: ✓ indicates ‘yes’- low risk of bias. ? indicates unclear – not enough information provided in the publication. × indicates ‘no’ – high risk of bias. n/a indicates this assessment was not applicable for this study type.