Table 2. Virulence factors identified in S. suis P1/7 membrane vesicles.

Identified proteins	Factor	Protein accession number	Gene accession number	Molecular weight	Function	References
Surface-anchored serine protease	SspA	C5VVK9	SSU1773	187 kDa	Subtilisin-like protease	[39, 40]
Surface-anchored DNA nuclease	SsnA	C5VVJ6	SSU1760	114 kDa	DNase	[41, 42]
Mac family protein	Ide	C5W022	SSU0496	124 kDa	IgM protease	[38]
Glyceraldehyde-3-phosphate dehydrogenase	Plr	C5VY36	SSU0153	39 kDa	Adhesin	[46]
Streptococcal histidine triad-family protein	HtpsC	C5VYR5	SSU1390	96 kDa	Unknown	[37]
Muramidase-released protein	Mrp	C5VVS8	SSU0706	136 kDa	Unknown	[43]
Surface-anchored amylopullulanase	ApuA	C5VVZ9	SSU1849	234 kDa	Adhesin	[44]
Enolase	Eno	C5VYJ5	SSU1320	47 kDa	Adhesin	[45]
Suilysin	Sly	C5VXY1	SSU1231	55 kDa	Hemolysin	[47, 48]