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. 2015 Jun 25;11(6):e1004942. doi: 10.1371/journal.ppat.1004942

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© 2015 Unciti-Broceta et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 5 — (a) IC₅₀ analysis. Free pentamidine (grey column); pentamidine-chNPs (red column) and NbAn33-pentamidine-chNPs (blue column). Errors bars indicate SEM from 3–9 independent experiments. Fold reductions are indicated in the graph. (b) Therapeutic effect in TbR25 acute infection mouse model. Survival (Kaplan-Meier plot) of female C57BL/6J mice infected with TbR25 (inoculum 2.5 x 10⁶ parasites).