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. 2015 Jun 25;10(6):e0130739. doi: 10.1371/journal.pone.0130739

Table 7. Nucleotide, Cofactors, and Vitamin Metabolism.

Super Pathway Sub Pathway Biochemical Name FH/FN NBH/NBN AH/AN NBN/FN AN/FN AN/NBN
Nucleotide Purine Metabolism Xanthine inosine 1.27 1.97 1.48 1.33 2.78 2.09
hypoxanthine 1.24 1.12 1.56 1.53 1.17 0.76
xanthosine 1.06 1.24 1.51 1 2.64 2.64
Purine Metabolism, Adenine adenosine 5'-diphosphate (ADP) 1.43 1.39 1.03 1.14 3.18 2.78
adenosine 5'-monophosphate (AMP) 1.23 2.35 0.69 1.06 21.37 20.12
adenosine 3'-monophosphate (3'-AMP) 0.98 0.6 1.19 2.76 0.21 0.08
  adenosine 2'-monophosphate (2'-AMP) 1.36 0.68 0.99 2.86 1.27 0.44
  adenosine 1.17 1.86 0.78 0.78 2.22 2.84
  adenine 0.65 2.83 1.95 0.69 3.69 5.39
  cyclic adenosine diphosphate-ribose 0.77 2.78 2.34 0.53 1.2 2.29
Purine Metabolism Guanine guanosine 3'-monophosphate (3'-GMP) 1.1 0.7 1.11 2.45 0.26 0.11
guanosine 1.09 1.23 1.45 1.63 1.62 0.99
guanine 0.98 1.21 2.31 1.61 0.65 0.41
Pyrimidine Metabolism Uracil uridine monophosphate (5' or 3') 1 1 0.92 1 1.09 1.09
uridine 1.3 1.35 1.36 1.52 1.42 0.93
uracil 1.1 1.81 2.44 0.56 0.37 0.66
  pseudouridine 0.69 0.62 1.02 1.58 0.66 0.42
  3-ureidopropionate 0.34 1.96 1.52 0.28 0.28 1
  beta-alanine 0.93 3.88 1.64 0.74 2.88 3.9
Pyrimidine Metabolism Cytidine cytidine 5'-monophosphate (5'-CMP) 1.44 2.92 0.78 0.74 4.36 5.92
cytidine-3'-monophosphate (3'-CMP) 1.29 1.9 1.21 1.25 0.57 0.45
cytidine 0.99 1.28 1.86 1.46 0.83 0.57
Purine and Pyrimidine Metabolism methylphosphate 1.2 1.82 1.63 1.06 1.76 1.66
Cofactors and Vitamins Nicotinate and Nicotinamide Metabolism nicotinamide 1.49 2.78 1.96 1.02 2.28 2.23
nicotinamide ribonucleotide (NMN) 1.19 5.33 1.92 0.27 1.07 3.97
nicotinamide adenine dinucleotide (NAD+) 0.36 4.22 1.44 0.14 3.12 22.92
nicotinamide adenine dinucleotide reduced (NADH) 1.39 6.72 0.44 0.52 34.33 66.3
  adenosine 5'diphosphoribose 1.09 1.53 1.47 0.84 10.73 12.7
Riboflavin Metabolism flavin adenine dinucleotide (FAD) 1.1 1.22 1.25 1.19 2.27 1.9
Pantothenate and CoA Metabolism pantothenate 1.11 2.22 2.12 0.75 0.45 0.6
Ascorbate and Aldarate Metabolism ascorbate (Vitamin C) 3.42 28.6 1.28 0.35 14.79 42.29
Tocopherol Metabolism alpha-tocopherol 1.55 1.11 1.09 2.8 8.29 2.96
Hemoglobin and Porphyrin Metabolism bilirubin (Z,Z) 1.92 1.26 1 1 1 1