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. 2015 Jun 25;10(6):e0130739. doi: 10.1371/journal.pone.0130739

Table 13. Top metabolites altered in adult carotid arteries in reponse to LTH.

Biochemical Name AH/AN p-value Biochemical Name AH/AN p-value
lauryl sulfate 8.68 0.0365 N-acetylalanine 1.44 0.0607
phosphoenolpyruvate (PEP) 5.98 0.0036 palmitate (16:0) 1.3 0.0519
4-hydroxybutyrate (GHB) 5.74 0.0009 glycerol 3-phosphate (G3P) 1.21 0.0765
glycerate 5.37 0.0008 myristate (14:0) 1.2 0.0945
ribose 4.86 0.0024 uridine monophosphate (5' or 3') 0.92 0.0162
glucose-6-phosphate (G6P) 4.66 0.0185 leucylglutamate 0.83 0.015
3-phosphoglycerate 4.1 0.0538 cysteine 0.81 0.0843
fructose-6-phosphate 3.96 0.035 serylphenyalanine 0.66 0.0255
mannose-6-phosphate 3.85 0.0215 hexadecanedioate 0.65 0.0019
pyruvate 3.78 0.0122 isoleucylglycine 0.62 0.0763
6-phosphogluconate 3.7 0.0847 leucylserine 0.61 0.0108
glycerol 2-phosphate 3.58 0.006 mead acid (20:3n9) 0.54 0.0607
pyrophosphate (PPi) 2.9 0.0839 threonylglutamate 0.39 0.0029
xylitol 2.82 0.0912 valylglycine 0.38 0.0054
3,4-dihydroxyphenethyleneglycol 2.47 0.0164 N-methyl proline 0.3 0.0082
uracil 2.44 0.0605 citrate 0.29 0.014
erythritol 2.38 0.0422 cholate 0.25 0.0428
1-methylimidazoleacetate 2.37 0.0003
cyclic adenosine diphosphate-ribose 2.34 0.0047
guanine 2.31 0.0939
fructose 2.29 0.0548
dihomo-linoleate (20:2n6) 2.26 0.0004
mannitol 2.2 0.0335
ribulose/xylulose 5-phosphate 2.2 0.086
hypotaurine 2.17 0.0841
chiro-inositol 2.14 0.0107
pantothenate 2.12 0.0228
ethanolamine 2.04 0.0696
beta-hydroxyisovaleroylcarnitine 2.02 0.0328
linoleate (18:2n6) 1.97 0.0044
adenine 1.95 0.0149
nicotinamide ribonucleotide (NMN) 1.92 0.0318
stearoyl sphingomyelin 1.88 0.0515
inositol 1-phosphate (I1P) 1.87 0.0483
cytidine 1.86 0.0246
homocitrulline 1.82 0.0724
urea 1.64 0.0576
methylphosphate 1.63 0.0174
1-stearoylglycerophosphoserine* 1.61 0.0514
cis-vaccenate (18:1n7) 1.57 0.0647
dihomo-linolenate (20:3n3 or n6) 1.56 0.0537
S-nitrosoglutathione (GSNO) 1.53 0.0156
glycerol 1.51 0.0192
xanthosine 1.51 0.0656
adenosine 5'diphosphoribose 1.47 0.0924