Fig 3. Simulations of the PUABM match key features of clinical images.

(A) Simulations achieved visual appearances with characteristics similar to each stage of PU development. The first row of clinical images come from the National Pressure Ulcer Advisory Panel (images from npuap.org, used with permission) and are of different subjects. Images in the second row are from people with SCI enrolled in a prospective study of PU at each stage. Irregular shapes and increasing nearby damage are observed in both sets of clinical data. (B) Numbers indicate days post-injury. Simulated ulcers evolve with visual characteristics that match PU progression observed in people with SCI. Two simulation time courses are matched against one patient from our study. We match key features: irregular shapes, nearby satellite ulcers (open arrows), jagged edges (solid arrows), and decreasing tissue health across the field.