Fig 3. Hierarchical clustering of expression profiles for genes in the KEGG proteasome pathway.

The Hierarchical clustering analysis was performed on gene expression data from Chung et al., 2008. Individual gene-related signals are increased (red), unchanged (white), or decreased (blue). The analysis clearly separates cases (brown group) from controls (light blue group) and reveals the up-regulation of proteasome genes in the SJS/TEN lesions.