Table 1. The top enriched KEGG pathways for low risk genetic variants ranked by normalized enrichment score (NES).

Pathway	#GSS	#GLE	ES	NES	PV	FDR
ABC transporters	44	23	0.6	3.4	0.001	0.06
Proteasome	43	21	0.4	2.6	0.004	0.25
Propanoate metabolism	32	13	0.5	2.5	0.002	0.25

Abbreviations: #GSS (gene set size for the pathway); #GLE (number of pathway genes in GSEA leading edge); ES (enrichment score), NES (normalized enrichment score), PV (p-value of ES), FDR (false discovery rate).