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. 2015 Jun 25;10(6):e0131563. doi: 10.1371/journal.pone.0131563

Table 5. Hepatic concentrations of metabolites in pigs fed a control, creatine supplemented or GAA supplemented diet for 18–19 days 1 .

Control Creatine GAA
nmol/g wet weight
Arginine 43.2 ± 4.6 64.3 ± 35.5 41.6 ± 4.1
Methionine 99.1 ± 38.4 99.3 ± 30.1 86.6 ± 28.5
SAM 56.9 ± 8.4b 66.5 ± 22.6b 31.9 ± 16.5a
SAH 15.1 ± 2.8 15.4 ± 2.6 18.3 ± 11.8
SAM/SAH 3.94 ± 1.24 4.35 ± 1.50 2.46 ± 1.68
SAM DPM 114 ± 28 127 ± 33 144 ± 47
PC (umol/g) 8.1 ± 2.2 8.5 ± 2.4 6.9 ± 2.9

1Data are means ± SDs; n = 6. Means with different superscripts are significantly different within rows, P < 0.05. DPM, disintegrations per minute; GAA, guanidinoacetate; PC, phosphatidylcholine; SAH, S-adenosylhomocysteine; SAM, S-adenosylmethionine