Fig 6. Histopathology of TMM001- vs PBS-treated mice 48 h post challenge.

H&E-stained lung (A, B) and spleen (C, D) of CSM001 (1.5 x 10⁵ CFU) challenged mice previously immunized with PBS (A, C) or TMM001 (1.5 x 10⁴ CFU) (B, D). Scale bar = 100μM. Histological scores were assigned for the liver (E), lungs (F), and spleen (G) tissue sections after microscopic examination. Mean ± SEM, representative of three animals, is plotted. Statistical significance was determined by the Mann-Whitney test. ^★ p ≤ 0.05.