Fig 2. Effect of acute curcumin on working memory, motor function and spatial reference memory in an Aβ1-42-treated rat model of Alzheimer's disease.

(A) The spontaneous alteration in the Y-maze. (B) The total arm entries in the Y-maze. (C) The total distance travelled in an open-field test. (D) Representative swim traces in the Morris water maze training trial. (E) The escape latency during the water maze training trials. (F) The time spent in the target quadrant in the probe task. n = 8 each group. * P < 0.05 and ** P < 0.01 compared with Aβ1–42 + saline group