Fig 3.
Malthusian parameter and pairwise competition estimates of fitness for S. aureus ciprofloxacin and fusidic acid susceptible and resistant mutants (A) Growth rates estimates from three S. aureus strains using a Bioscreen (BS, red bar) and BioTek (BT, black bar) plate readers. SA is an antibiotic sensitive strain, SA-CIP is a ciprofloxacin resistant strain and SA-FUS is a fusidic acid resistant strain. (B) Malthusian parameters relative to wild type (SA), (Bioscreen red BioTek black) and Bootstrap-calculated confidence intervals. (C) Changes in the ratio of the antibiotic resistant mutants and SA WT in pairwise competition SA-CIP (black) and SA-FUS (blue), mean and standard deviation of the ratios from three independent competition experiments.