Fig 4. Malthusian parameter and pairwise competition estimates of fitness for Pseudomonas aeruginosa ciprofloxacin susceptible and resistant mutants in LB and glucose-limited minimal medium.
(A) Estimates of the absolute MP of WT and PA-CIP obtained with a Bioscreen (red bars) and BioTek (black bar) plate readers. (B) MP of PA-CIP of relative to wild type P. aeruginosa in glucose-limited minimal medium and LB, Bioscreen red and BioTek black. (C) Pairwise competition, ratio of PA-CIP strain relative to wild type in LB and minimal medium, mean and standard deviation of the ratios from three independent competition experiments. (D) Longer term changes in OD of CIP resistant and sensitive strains in minimal medium and LB, Bioscreen data.