Fig 5. Malthusian parameter and pairwise competition estimates of fitness for E. coli antibiotic sensitive and resistant mutants and transconjugants in LB and glucose-limited minimal medium.

(A) Estimates of the MP in minimal medium (left panel) and broth (right panel), Bioscreen (BS, red bar) and BioTek (BT, black bar). (B) Relative to WT growth rates of BAM-Nal and BAM-JCA in minimal and broth. (C) Ratio of antibiotic sensitive (WT) and resistant mutants in pairwise competition; BAM-Nal and WT (blue) and BAM-JCA and WT (black). Mean and standard error for 3 independent cultures from the same initial mixture.