Table I.
Characteristics of Patients with Persistent Fever and Neutropenia (n = 135)
Characteristic | |
---|---|
Age at first episode (years, median, IQRa) | 8.2 (3.2–15.0) |
Male (n, %) | 89 (66) |
Hematologic malignancy (n, %) | 84 (62) |
Acute lymphoblastic leukemia | 39 (29) |
Acute myelogenous leukemia | 26 (19) |
Otherb | 19 (14) |
Stem cell transplant recipient (n, %)c | 107 (79) |
Transplant indication (n, %) | |
Hematologic malignancy | 56 (42) |
Solid tumor malignancy | 26 (19) |
Primary immunodeficiency | 10 (7) |
Otherd | 15 (11) |
Interquartile range.
Includes 8 patients with myelodysplastic syndrome, 6 with lymphoma, 3 with juvenile myelomonocytic leukemia and 2 with biphenotypic leukemia.
Eight patients received multiple stem cell transplants.
Includes 6 patients with aplastic anemia/bone marrow failure syndromes, 4 with genetic/metabolic disorders, 3 with hemoglobinopathies and 2 with hemophagocytic lymphohistiocytosis.