Table 1. Effect of melatonin supplementation on circadian parameters in C57 mice across the entire 28-day study period.

Values obtained from non-orthogonal spectral analysis of home cage locomotor activity across all 28 days of the study. Values are presented as mean (SEM) and n = 15 control and 16 melatonin supplemented animals.

28 Days Combined
	Control	Melatonin
Amplitude	8.4 (0.9)	7.9 (0.8)
SD Amplitude	2.6 (0.2)	2.7 (0.1)
Time of Nadir	12.8 (1.9)	11.8 (1.4)
SD Time of Nadir	2.7 (0.3)	2.7 (0.4)
Time of Peak	19.7 (1.3)	21.7 (1.5)
SD Time of Peak	3.1 (0.3)	3.9 (0.3)