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. 2014 Jun 23;17(1):136–144. doi: 10.1093/neuonc/nou112

Table 4.

Multivariate analysis of independent prognostic factors associated with time to distance recurrence and time to local recurrence. Result of competing risk analyses.

Parameters TTD
TTL
HR 95% CI P HR 95% CI P
Radiological appearance
 Diffuse vs focal N/A 2.1 0.96–4.7 .064
Ki67 labeling index
 ≥15% vs <15% 8.6 1.3–58.7 .029 N/A
CD133 expression
 High vs low 1.0 0.30–3.6 .96 1.4 0.49–4.3 .51
IDH
 Wild-type vs mutated 6.6 1.3–34.7 .025 0.89 0.35–2.2 .80
MGMT
 Unmethylated vs methylated 1.4 0.36–5.3 .64 N/A
1p19q
 Retain vs loss N/A 3.9 1.3–11.7 .016

Abbreviations: CI, confidence interval; HR, hazard ratio; N/A: not applicable; TTD, time to distant recurrence; TTL,time to local recurrence.