Table 3.
Univariate survival analysis and multivariate Cox regression analysis for type of surgery and age at initial diagnosis for different f/u groups
Postradiation Scan | Parameter | Number of Patients, Died/Total | Univariate Survival Analysis |
Multivariate Cox Regression Analysis |
|||
---|---|---|---|---|---|---|---|
P, Log-Rank | Median, mo (95% CI) | Hazard Ratio (95% CI) | P | ||||
First f/u* | Age | ≤ Median age | 17/20 | .585 | 16.6 (12.9–20.4) | 1.2 (0.6–2.3) | .65 |
> Median age | 21/25 | 16.4 (10.8–22.0) | |||||
Surgery | Gross total resection | 21/23 | .952 | 15.7 (11.7–19.6) | 1.1 (0.6–2.2) | .76 | |
Subtotal resection/biopsy | 17/22 | 17.0 (11.9–22.0) | |||||
Progression | PsP | 2/6 | .03 | 29.9 (12.7–47.0) | 3.0 (1.0–8.8) | .044 | |
True progression | 40/45 | 14.3 (11.9–16.8) | |||||
Second f/u | Progression | PsP | 2/2 | NA | 24.5 (23.5–25.5) | NA | NA |
True progression | 14/15 | 14.0 (9.8–18.3) | |||||
Third f/u | Progression | PsP | 0/1 | NA | 19.0 | NA | NA |
True progression | 6/8 | 20.1 (13.4–26.8) | |||||
Fourth f/u | Progression | PsP | 0 | NA | NA | NA | NA |
True progression | /78 | 21.3 (17.0–25.6) | |||||
First, second, third, and fourth f/u's cumulatively | Age | ≤ Median age | 34/41 | .212 | 18.3 (15.5–21.1) | 1.5 (0.9–2.5) | .102 |
> Median age | 33/38 | 16.1 (12.4–19.9) | |||||
Surgery | Gross total resection | 30/36 | .52 | 19.1 (14.4–23.8) | 1.4 (0.8–2.3) | .19 | |
Subtotal resection/biopsy | 37/43 | 16.2 (13.7–18.9) | |||||
Progression | PsP | 6/9 | .012 | 29.6 (16.5–42.6) | 2.9 (1.2–6.8) | .014 | |
True progression | 61/70 | 15.8 (13.8–17.7) |
Abbreviation: NA, not applicable.
P-values below .05 are boldfaced.