Fig. 6.
DDR studies with known Wnt inhibitors using cell lines CHLA-04-ATRT, CHLA-05-ATRT, CHLA-06-ATRT, NSC, HEK, and HeLa. The representative DDR curves shown are (A) WntC59, (B) niclosamide, (C) casin, and (D) pyrvinium. The IC50 values for these inhibitors are shown in (E). (F) shows a schematic indicating the Wnt inhibitors used in this study and their known targets.