. 2014 Oct 9;17(4):588–595. doi: 10.1093/neuonc/nou293

Table 3.

Univariate analysis for local control, PFS, and OS

Parameters	Cumulative Proportion of Patients With Local Tumor Control (SE)	P	Cumulative Proportion of Patients With Local and Distant Tumor Control (SE)	P	Cumulative Proportion of Surviving Patients (SE)	P
Age, y		<.001		<.001		.11
<36	0.40 (0.06)		0.30 (0.06)		0.86 (0.07)
≥36	0.84 (0.05)		0.81 (0.05)		0.64 (0.12)
Gender		.22		.29		.26
Female	0.68 (0.06)		0.59 (0.07)		0.96 (0.03)
Male	0.56 (0.06)		0.50 (0.06)		0.89 (0.05)
Tumor location		.66		.58		.46
Lumbosacral/filum terminale	0.68 (0.04)		0.53 (0.05)		0.75 (0.07)
Cervicothoracic	0.75 (0.21)		0.75 (0.21)		1.0
Metastasis at diagnosis		.28		.03		.03
No	0.77 (0.07)		0.54 (0.05)		0.77 (0.07)
Yes	0.50 (0.21)		0.66 (0.20)		0.50 (0.30)
Tumor size		.28		.35
<20 mm	0.59 (0.11)		0.52 (0.11)		1.0	.17
≥20 mm	0.80 (0.07)		0.58 (0.12)		0.89 (0.07)
Symptoms		.20		.52		.16
Unilateral	0.36 (0.25)		0.30 (0.22)		0.93 (0.04)
Bilateral	0.74 (0.05)		0.58 (0.07)		0.95 (0.02)
Initial treatment modality		.006^a		.005^a		.99^a
Surgery alone	0.45 (0.08)		0.38 (0.08)		0.92 (0.03)
Surgery and standard-dose RT^b	0.71 (0.08)		0.56 (0.08)		0.86 (0.06)
Surgery and high-dose RT^c	0.66 (0.10)		0.66 (0.11)		0.71 (0.15)
Extent of surgery		.02		.02		.10
GTR	0.68 (0.06)		0.63 (0.07)		0.90 (0.04)
STR or biopsy	0.55 (0.06)		0.45 (0.06)		0.70 (0.10)
Salvage treatment		<.001		.86		.87
Yes	0.03 (0.02)		0.02 (0.02)		0.74 (0.09)
No	0.55 (0.06)		0.11 (0.10)		0.88 (0.10)

Abbreviation: STR, subtotal removal.

^aSurgery vs surgery + standard-/high-dose RT.

^b<50.4 Gy.

^c≥50.4 Gy.