Table 4.
Predictor | Variable | HR | 95% CI | P value |
---|---|---|---|---|
Supratentorial brain | ||||
Age at diagnosisa | ≥37 y | 1 | ||
<36 y | 0.61 | 0.26–1.44 | .258 | |
Tumor grade | Grade II | 1 | ||
Grade III | 2.21 | 0.89–5.48 | .086 | |
Initial treatment*,b | GTR | 1 | ||
STR | 1.49 | 0.17–12.75 | .718 | |
STR + radiation | 5.38 | 1.78–16.26 | .003 | |
GTR + radiation | 1.39 | 0.5–3.67 | .506 | |
Infratentorial brainc | ||||
Age at diagnosis | ≥48 y | 1 | ||
<47 y | 1.47 | 0.62–3.79 | .384 | |
Tumor grade* | Grade II | 1 | ||
Grade III | 7.30 | 1.30–29.34 | .027 | |
Initial treatment*,b | GTR + radiation | 1 | ||
GTR | 12.80 | 1.50–1690.44 | .014 | |
STR | 34.37 | 3.69–4658.06 | <.001 | |
STR + radiation | 12.12 | 1.32–1627.69 | .023 | |
Spine | ||||
Age at diagnosis | ≥45 y | 1 | ||
≤44 y | 2.93 | 0.95–9.05 | .061 | |
Tumor grade | Grade II | 1 | ||
Grade I | 1.19 | 0.43–3.29 | .742 | |
Grade III | 1.94 | 0.39–9.64 | .416 | |
Initial treatment*,b | GTR | 1 | ||
STR | 1.54 | 0.32–7.55 | .592 | |
STR + radiation | 5.01 | 1.84–13.69 | .002 | |
GTR + radiation | 3.84 | 0.46–32.10 | .215 |
Abbreviations: CI, confidence interval; GTR, Gross total resection followed by observation; GTR + radiation, gross total resection followed by radiation; HR, hazard ratio; STR, subtotal resection followed by observation; STR + radiation, subtotal resection followed by radiation.
aBased on median age.
bInitial treatment variable is categorized as gross total resection followed by observation, subtotal resection followed by observation, subtotal resection followed by radiation, and gross total resection followed by radiation.
cwith Firth's penalized method.
*Significant at P < .05.