Table 1.
Patient demographics and treatment
| Patient | Age at Diagnosis | Sex | Tumor Location/ Extent of Resection | RT | Site of Recurrence | Age at Recurrence | Treatment Duration (cycles) | PFS (months) | OS (months) | Best Response |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 1.39 | Male | RF/STR | F 55.8 Gy | R thalamus | 6.92 | 5 | 3.2 | 8.4 | SD |
| 2 | 4.87 | Female | PF/GTR | CSI+ | Spine | 9.04 | 23 | 16.4a | 16.4a | PR |
| 3 | 3.26 | Female | PF/GTR | CSI+ | Spine, CSF | 4.75 | 14 | 15.1 | 21.8 | PR (CSF cleared & spinal lesion decreased in size) |
| 4 | 1.75 | Male | Pineal/GTR | FP 59.4 Gy | Brainstem | 3.83 | 34 | 23.6a | 25.6a | CR |
Abbreviations: CSI+, craniospinal radiation 23.4 Gy with boost to tumor bed to 55.8 Gy; F, focal irradiation with photons; FP, focal irradiation with protons; GTR, gross total resection; OS, overall survival; PF, posterior fossa; PFS, progression-free survival; RF, right frontal lobe; RT, radiation therapy; SD, stable disease; STR, subtotal resection.
aCensored.