Table 3. Correlations Among Major and Minor Apo(a) Isoforms, OxPL-apoB, Lp(a) and Other Biomarkers of Oxidized Lipoproteins.
Trait | Spearman's rho | Major isoform |
Minor Isoform |
Lp(a) | OxPL-apoB | IgG ApoB-IC |
IgM ApoB-IC |
IgG MDA-LDL |
IgM MDA-LDL |
IgG CuOxLDL |
IgM CuOxLDL |
---|---|---|---|---|---|---|---|---|---|---|---|
Major isoform | CorrCoeff | 0.48 | -0.48 | -0.49 | -0.02 | 0.02 | 0.02 | 0.08 | -0.02 | 0.07 | |
P-Value | <0.001 | <0.001 | <0.001 | 0.74 | 0.83 | 0.82 | 0.21 | 0.78 | 0.30 | ||
| |||||||||||
Minor Isoform | CorrCoeff | -0.015 | -0.30 | -0.05 | -0.11 | 0.07 | 0.05 | 0.10 | 0.02 | ||
P-Value | 0.021 | <0.001 | 0.45 | 0.12 | 0.29 | 0.48 | 0.13 | 0.74 | |||
| |||||||||||
Lp(a) | CorrCoeff | 0.57 | 0.20 | 0.07 | 0.10 | 0.06 | 0.16 | 0.08 | |||
P-Value | <0.001 | <0.001 | 0.19 | 0.05 | 0.26 | 0.001 | 0.14 | ||||
| |||||||||||
OxPL-apoB | CorrCoeff | 0.26 | 0.11 | 0.06 | 0.09 | 0.09 | 0.09 | ||||
P-Value | <0.001 | 0.036 | 0.29 | 0.09 | 0.08 | 0.10 | |||||
| |||||||||||
IgG ApoB-IC | CorrCoeff | 0.22 | 0.69 | 0.13 | 0.59 | 0.14 | |||||
P-Value | <0.001 | <0.001 | 0.010 | <0.001 | 0.008 | ||||||
| |||||||||||
IgM ApoB-IC | CorrCoeff | 0.22 | 0.69 | 0.24 | 0.72 | ||||||
P-Value | <0.001 | <0.001 | <0.001 | <0.001 | |||||||
| |||||||||||
IgG MDA-LDL | CorrCoeff | 0.23 | 0.80 | 0.21 | |||||||
P-Value | <0.001 | <0.001 | <0.001 | ||||||||
| |||||||||||
IgM MDA-LDL | CorrCoeff | 0.25 | 0.88 | ||||||||
P-Value | <0.001 | <0.001 | |||||||||
| |||||||||||
IgG CuOxLDL | CorrCoeff | 0.28 | |||||||||
P-Value | <0.001 |
The correlation analysis was carried in out in twins pairs with complete data on isoforms, OxPL-apoB and other biomarkers of oxidized lipoproteins (n=224).