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. 2015 Jun 26;10(6):e0131066. doi: 10.1371/journal.pone.0131066

Fig 1. TazNeo ES cells have a reduction of cardiolipin levels.

Fig 1

(A) Diagram of mouse taz wild-type and TazNeo alleles. While all 10 exons of the wild-type gene are normally expressed, the insertion of the neo cassette prevents proper expression of Taz RNA (S1 Fig). (B) Cardiolipin profile of TazNeo (bottom) ES cells confirms Taz deficiency by showing the accumulation of MLCL and reduction of mature CL as compared to control (top).