Table 2.
Frequency of the predicted human immunodeficiency virus drug resistance mutations
| Resistance mutation (n = 3,235) | No. of patients (%) |
|---|---|
| NRTI mutation | |
| M184V/I | 1,153 (35.64) |
| T215Y/F | 879 (27.17) |
| M41L | 595 (18.39) |
| D67N | 395 (12.21) |
| K70R/E/G | 330 (10.20) |
| L210 W | 329 (10.17) |
| K219E/Q | 324 (10.02) |
| L74I/V | 118 (3.65) |
| V75I/M | 110 (3.40) |
| Q151 M | 93 (2.87) |
| A62 V | 74 (2.29) |
| F116Y | 67 (2.07) |
| K65R/N | 51 (1.58) |
| F77L | 30 (0.93) |
| Y115F | 9 (0.28) |
| ≥1TAM | 1,369 (42.32) |
| TAM-1 | 290 (8.96) |
| TAM-2 | 149 (4.61) |
| TAM-1/TAM-2 | 10 (0.31) |
| Q151 M complex | 13 (0.40) |
| M184 V/I + TAMs | 691 (21.36) |
| NNRTI mutation | |
| K103 N/S | 1,127 (34.84) |
| Y181C/V/I | 713 (22.04) |
| G190A/S/E | 590 (18.24) |
| K101E/P | 247 (7.64) |
| V108I | 225 (6.96) |
| V106A/M | 177 (5.47) |
| Y188L/C/H | 140 (4.33) |
| F227L/C | 121 (3.74) |
| K238T | 117 (3.62) |
| V179D/E/F | 93 (2.87) |
| P225H | 63 (1.95) |
| A98G | 53 (1.64) |
| L100I | 11 (0.34) |
| P236L | 1 (0.03) |
| PI mutation | |
| M46I/L | 22 (0.68) |
| V82F | 11 (0.34) |