Table 1.
MTHFR C677T and A1298C genotype frequencies and the CL/P risk
| Genotype | Controls (n=215) N (%) | Cases (n=61) N (%) | p-value | OR (CI 95%) |
|---|---|---|---|---|
| C677T/CC | 114 (53) | 21(34.4) | -- | Reference group |
| C677T/CT | 72 (33.5) | 18 (29.5) | 0.389 | 1.35 (0.68–2.7) |
| C677T/TT | 29 (13.5) | 22 (36.1) | 0.001 | 4.1(2–8.5) |
| Controls (n=189) N (%) | Cases (n=65) N (%) | p-value | OR (CI=95%) | |
| A1298C/AA | 73 (38.6) | 24 (36.9) | Reference group | |
| A1298C/AC | 92 (48.7) | 34 (52.3) | 0.705 | 1.124 |
| A1298C/CC | 24 (12.7) | 7 (10.8) | 0.807 | 0.887 |
(CI= Confidence Interval, N= Number, OR= Odds Ratio)