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. 2015 Jul;185(7):2000–2011. doi: 10.1016/j.ajpath.2015.03.022

Figure 6.

Figure 6

Postnatal Col5a2+/− heterozygotes have abnormalities in collagen fibril morphology. Transmission electron micrographs of collagen fibrils in cross section (A and D) and longitudinal section (B and E) in the skin of P50 Col5a2+/+ (A and B) and Col5a2+/− (D and E) mice. A thicker fibril with irregular contours is marked by an asterisk. Fibril diameter distributions were a mean of 105.2 nm, a median of 91.6 nm, and an SD of 15.72 nm for postnasal day 50 Col5a2+/+ mice (C) and a mean of 101.8 nm, a median of 89.7 nm, and an SD of 13.3 nm for Col5a2+/− mice (F). n = 38 (C); n = 38 (F).